Posts Tagged ‘osteoporosis’

Body Fat & Weight

Doctors and exercise experts agree that the percentage of body fat you carry around is more important than how much you weigh.  (Additionally, muscle–which is “healthy” tissue–weighs more than fat, though it takes up less space.

So, the bathroom scale isn’t the best measure of your health and fitness.

A body composition test measures what percentage of your total weight is body fat.  Everything else is lean body mass (muscles, bones, ligaments, tendons, skin and organs).

How Much Body Fat is Too Much?

Of course, you do need some body fat, to help carry on normal body functions.  For instance, fat helps protect your internal organs from injury.  However, a high percentage of body fat can lead to heart disease, diabetes and other illnesses.  Experts recommend men carry at least 5 percent body fat; women should carry at least 12 percent.  But those are just bare minimums for maintaining health.

The recommended body fat level for most men is around 15 percent.  For women (who have higher body fat levels) a 22 percent range is considered healthy.  Generally speaking, the more fat you carry (above the recommended levels), the worse shape you’re in.  Men usually carry their body fat in their abdomen; women carry fat in their arms and their thighs.  And statistics show that Americans are increasingly carrying far too  much fat.

In 1996, the Journal of the American Medical Association reported that–between 1980 and 1991 an additional 8 percent of American population became over fat.  By 2011 the percentage of over weight Americans has hit 68 percent.  This means that 7 out of 10 Americans are now over weight or obese.  The percentage of children that are over weight or obese is between 30 and 40 percent (depending on ethnicity and gender).  According to the U.S. Surgeon General Office the over 300,000 people are dying every year as a result of being too fat.  From diseases to heart attaches to actually choking to death.   It is unhealthy to be fat.

The reasons given for these loses in “the battle of the bulge” are simple: the American people– adults and kids–are eating too much and not getting enough exercise.  Fad diets are not helping, though Americans spend an estimated $40 billion a year on trying to control their waistlines.  Statistics show that as much as 95 percent of those people who go on a diet regain all their weight (meaning body fat) back, often times increasing their body fat levels.

If you are concerned about your percentage of body fat, or that or your children, you should seek the guidance of a physician in planning an exercise program and low-fat diet.  Under no circumstances should you put children on a diet without the advice of a doctor.

How We Lose Muscle, and Gain Fat

One of the major problems for inactive adults is the fact that–without regular weightlifting (resistance training) of some kind–the muscles you were born with and develop through your active teens and twenties, will rapidly start to be replaced by fat.

As a general rule, inactive women and men start losing muscle at the rate of half a pound a year.  This half-pound annual loss of muscle also sees about a pound and a half of fat gained each year.  Scientific studies have shown it does not matter if you’re doing regular aerobics, or if you overall body weight remains the same, you will be losing muscle and gaining body fat as yo approach middle age.

By the time you reach 70, most people will have lost about 30 percent of their muscle, unless they have taken steps to prevent (or reverse) the atrophy of their muscles.

Resistance training is the only way to maintain and re-build muscle.   For every pound of fat you replace with muscle, your body will burn about 50 extra calories a day, even when you are at rest.  An additional benefit of weightlifting is the strengthening of bones (part of your lean body mass), which helps guard against osteoporosis.

Where to Get Tested

If you are interested in getting a body composition test, talk to your doctor, or someone at a sports clinic.  They routinely measure clients’ body composition, using a variety of methods.

Many doctors and professionals often measure body fat by using hand-held calipers.  A hydrostatic test entails submerging clients in a pool for “underwater weighing”.  And Magnetic Resonance Imaging (an MRI) measures fat and muscle by taking X-ray like “pictures” of soft body tissues, muscle, and bone, rendering each of these in different tone, or colors.

The most sensible approach to reducing your percentage of body fat is do eat a healthful, low-fat diet, and to adopt a regular exercise program that includes building and maintaining your muscles.

 

 

 

You Are Never Too Old To Exercise

Aging is not age alone.  It’s also a person’s lifestyle, and that is true for the mind as well as the body.

Studies show that exercise maintains your thinking agility and cuts your risk of osteoporosis, heart disease and diabetes.

The American College of Sports Medicine urges older people to do strength training.  Walking is simply not enough.

Soloflex has, for years, urged customers and future customers to “use if or lose it”.  If you sit around and do nothing , you will become weak, no matter what your age.

Strength training is good medicine for depression and improving your life.  Yes, exercise can help you feel and look better, no matter what your age.

What are you waiting for?

For more great information on this please read Colin Hoobler’s article from The Oregonian here.

These Drugs Poison Your Bones

Al Sears, MD
11903 Southern Blvd., Ste. 208
Royal Palm Beach, FL 33411

January 25, 2011

Dear Jerry,

Would you use a drug that gives you the problem it’s supposed to prevent?

Well, that’s exactly what’s going on with the new osteoporosis drugs.

Fosomax, Boniva, Reclast, Actonel… these medications are supposed to help stop you from getting bone fractures as you get older. But we now have evidence that they cause bone breaks.

Researchers studied women taking these medications – called bisphosphonates – who experienced some sort of fracture. Over 65 percent had the same rare fracture in the same area of their thigh bones. And these were the women who had been on the drugs for the longest periods.1

Plus they’ve also found that if you’re on the drugs for a long time and you do get a bone break, you’ll heal very slowly. Sometimes it can take two years!

It’s another example of how modern medicine doesn’t learn from its mistakes. They refuse to take a whole-body approach to healing. Instead they opt to treat individual symptoms with drugs designed only for those symptoms.

And bone density drugs are a perfect example of this. I’ll tell you how they work in a moment, but first I want to tell you a little bit about how your body makes bone…

Your bones have cells called osteoclasts. Their job is to remove old bone tissue. This allows the bone to grow strong because other cells called osteoblasts then rebuild the bone.

With osteoporosis and other bone diseases, there is an imbalance … either your osteoblasts aren’t making new cells fast enough, or osteoclasts are removing too much tissue.

So drug companies came up with a way to stop osteoclasts from removing the old tissue, which also artificially increases your bone density: bisphosphonate drugs.

To read the rest of this article here

Soloflex Whole Body Vibration

erin ad on platform 2

Valuable Soloflex Information

Soloflex4resizeSoloflex was established in 1978.  Soloflex is a brand synonymous with quality, originality, beauty and fitness.  Soloflex pioneered infomercial advertising on cable TV, forever etching the brand name into Americans minds.  A survey done in 1992 indicated a brand recognition of 92%, the same as Bill Clinton’s that year.  Alone, Soloflex created the home fitness industry and most of the direct-response marketing strategies still used today.  Soloflex has always been family owned.   Our products are built to last a lifetime, all made in America.   Over one and a half million Soloflex exercise devices have been sold.   Total sales to date are approximately $1 Billion.  We have never had a recall.

Soloflex equipment has always met the demands of serious bodybuilders.  Many home gyms on the market today have a poor reputation, lacking quality and durability. We never understood the wisdom of lifting heavy weights with flimsy equipment.   The whole point of a weightlifting machine is safety.

The original Soloflex home gym.

The Soloflex machine has broad appeal because it makes weightlifting safe to do at home, alone.  Not spotter is required while using the Soloflex. The Soloflex machine is weight plate adaptable for those who want to safely add free weights to the resistance straps.  The machine allows proper form and range of motion on all exercises.  The free floating barbell arm recreates the natural movement free weights offer which is important for proper form and balance.  The Soloflex machine has been endorsed by Arnold Schwarzenegger, Frank Zane (3 time Mr. Olympia), Nordine Zouareg (Mr. Universe), Gale Sayers (NFL running back), and Mitch Gaylord (Olympic gold medalist).   The Soloflex Muscle Machine is priced from $1250 to $1550 + freight.

The Soloflex WBV Platform.

platformOur Whole Body Vibration Platform, unlike the others, was designed to exercise on.  We have been in production with the WBV platform for approximately 6 years.  We have sold over 75,000. One only need stand on the platform for short periods a few times a week to see improvements.   After research at SUNY with funds provided by NIH, NASA and the U.S. Army, WBV has demonstrated its effectiveness for the treatment of osteoporosis, an alternative to drugs like Fosamax, (a $5 billion/yr market).   WBV works as advertised.   Ours is affordably priced for home use at $445 + freight.

Very Important Information All People Should Know

The “Calcium Lie” Every Woman Should Know About

Posted By Dr. Mercola | December 21 2010 | 72,722 views

By Dr. Mercola

osteoporosisOsteoporosis is a disease characterized by porous and fragile bones. It affects 44 million Americans, striking 1 in 3 women, and 1 in 5 men. Those with osteoporosis are at increased risk of height loss, fractures of the hips, wrists and vertebrae, and chronic pain.

If you’ve been led to believe that the key to preventing osteoporosis is increasing your calcium intake and starting on a regimen of pharmaceutical drugs, you’re not alone.

I’m here to lead you past all of the confusing and conflicting information about osteoporosis and down a safer, more effective road to preventing bone loss and osteoporosis.

Read on to learn the truth about osteoporosis and calcium deficiency, what vitamins can make a real difference, and the surprising connection between bone loss and Alzheimer’s disease.

The Truth about Osteoporosis and Calcium Deficiency

I’m sure you’ve heard that the cause of osteoporosis and the key to its prevention revolve around calcium, right?

Unfortunately, nothing could be further from the truth.

Dr. Robert Thompson, M.D., wrote an entire book on this subject called, The Calcium Lie, which explains that bone is comprised of at least a dozen minerals and the exclusive focus on calcium supplementation is likely to worsen bone density and increase your risk of developing osteoporosis!

As mentioned in this previous article, Dr. Thompson recommends the use of unprocessed salt as a far healthier alternative to calcium supplementation.

I recommend using Himalayan salt as it is an excellent way to feed your body the trace minerals it needs to function optimally.

Why Sally Field Could be Setting Herself Up for Osteoporosis with Boniva

If you’ve been prescribed an osteoporosis drug such as Fosamax, Actonel or Boniva, it is very important that you understand how these drugs work before putting them into your body.

Web MD describes biphosphonate drugs as:

“…antiresorptive medicines, which means they slow or stop the natural process that dissolves bone tissue, resulting in maintained or increased bone density and strength.”

I’m sorry to say, you’re only getting half the story here. Using these types of pharmaceutical drugs is the worst way to attempt to treat or prevent osteoporosis and I’ll tell you why.

Even though they will increase your bone density, these drugs are poison!

They work by killing off certain cells in your bones called osteoclasts. Osteoclasts destroy the bone as part of the natural bone regeneration process. Killing off these cells means you are left with only osteoblasts, which will increase bone density but not bone strength.

As a result, your bones lose their natural ability to build new bone and readjust to the constantly changing forces applied.

Now you have thicker bones with less strength, which actually increases your risk of bone fractures. Additionally, these drugs have been linked to some terrible side effects, including increased risk of ulcers and:

Another disturbing fact?

Fosomax is in the same chemical class (phosphonate) as the soap scum cleaner you use in your bathroom! I’m sorry to say, it isn’t surprising that the pharmaceutical companies have never put that little tidbit of information on your prescription drug label.

Steer Clear of Steroids

According to a study done at Washington University School of Medicine in St. Louis, there is a strong link between osteoporosis and the use of steroids:

“High-dose cortisone is the second most common cause of osteoporosis, and we currently have no real treatment for this serious side effect,” says senior author Steven L. Teitelbaum, M.D., Messing Professor of Pathology and Immunology.

“Given how frequently these drugs are used to treat many different conditions, that’s a major clinical problem.”

The conclusion of the study revealed that although the steroid cortisone appears to inhibit the ability of osteoclasts to dismantle old bones in genetically normal mice, the inability of the skeletal structure to renew itself may cause bones to weaken dramatically from aging and stress.

If you suffer from an autoimmune disease such as rheumatoid arthritis, asthma, multiple sclerosis or chronic obstructive pulmonary disease, click on the links above for natural alternatives for healing.

On the other hand there is one steroid hormone that will likely help build bone and that is progesterone. Many pre and post menopausal women are deficient in this important hormone.

Gluten Intolerance and Bone Loss

Is your stomach often upset?

Chronic gas, nausea, bloating, diarrhea, constipation and brain fog could all be signs of an undiagnosed gluten intolerance.

Gluten is a protein found in grains such as wheat, rye and barley. According to statistics from the University of Chicago Celiac Disease Center, an average of one out of every 133 otherwise healthy people in the United States suffer from celiac disease (CD) but previous studies have found this number could be as high as 1 in 33 in at-risk populations.

Those with undiagnosed gluten intolerance often have malabsorption of nutrients due to chronic intestinal damage. This means that your body is unable to optimally take nutrients from food and distribute them throughout your body.

This malabsorption of nutrients can lead to osteoporosis.

If you often experience the above-mentioned symptoms, a gluten free diet may be the key you need to experience great health, perhaps for the first time in your life.

My book, The No Grain Diet, explains, in detail, the damaging health effects of sugars and grains, even to those who do not have a gluten intolerance.

Other Foods that Lead to Bone Loss

Processed and fast foods are the worst stuff you can put into your body. In order for your body to function optimally, it needs the type of balanced diet that I suggest in the next section.

Processed foods such as potato chips, french fries, microwaveable “meals”, soda and candy contain very little nutrients and are chock full of undigestible fats and dangerous additives such as high fructose corn syrup, aspartame and preservatives.

If you think switching from a mainly processed food diet to a healthy, nutritious one will be next to impossible, I’m here to tell you it’s easier than you think. In my previous article, I explain how to wean yourself off processed foods in 7 easy steps and how to give your body what it’s really craving.

When cooking, I advise you to avoid most all omega-6 based oils such as corn, safflower or soy oil. These oils are loaded with highly processed, damaged omega 6 fats, which contribute to inflammation in your body.

Instead, I recommend using healthful olive- and coconut oils. For more information, see my video on the health benefits of these oils.

Foods that Prevent Bone Loss

I recommend eating a wide variety of organic, preferably locally grown vegetables to get a proper balance of essential vitamins and minerals into your body. An easy way to increase the amount of vegetables in your diet is vegetable juicing.

It is a highly effective way to obtain the most potent nutrition and it’s easy for your body to digest and absorb.

Remember, it is important that you eat according to your nutritional type because the diet that works for one person may not work for another. Take a moment to take my FREE nutritional typing test to help determine your nutritional type, and the type of foods that are ideal for your personal biochemistry. We used to charge $29 to take this test but it was so important we decided to now offer it at no charge.

One important food that has been shown to help decrease bone loss and osteoporosis is onions. As I mentioned in my previous article, a study done on the effect of onions on laboratory rats proved promising.

Prevent Bone Loss with Appropriate Sunshine Exposure

The health benefits of vitamin D cannot be overstressed. An alarming number of people in the United States are vitamin D deficient, and vitamin D deficiency can lead to a host of health problems, including osteoporosis.

Despite what you may have heard, appropriate sunshine exposure is not bad for you. It is healthy and necessary. Just 15 to 20 minutes of sun exposure per day can make a dramatic improvement in your health, and appropriate sun exposure is the ideal way to maintain your vitamin D levels in the optimal range. Alternatively, you can use a safe tanning bed.

However, if neither of those options are available to you, the next option is to take an oral vitamin D3 supplement. Typical adult doses for vitamin D range from 5 to 10,000 units per day.

Keep in mind that it is very important to get your vitamin D levels checked by a qualified lab (I recommend LabCorp) to avoid under- or overdosing.

An optimal blood level of vitamin D for a healthy adult is between 50-70 ng/ml.

The Importance of Omega-3 for Strong, Healthy Bones

Omega 3 is another essential nutrient your body needs in order to prevent both physical and mental illness, inflammation and osteoporosis. As I mentioned in a previous article, The British Journal of Nutrition recently published a study stating that the Omega fat, DHA appears to constitute marrow and enhance bone mineral content.

Unfortunately, omega-3 deficiency is on the rise and has been revealed as the sixth biggest killer of Americans. It has been reported to increase risk of death from ALL causes and accelerate cognitive decline.

While plant-based omega-3 fats such as those found in flax seed are highly beneficial, on account of their high alpha-linolenic acid (ALA) content, animal-based omega-3 fats contain two crucial ingredients you are not getting from plants: docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).

Ideally, you would receive all the animal based omega-3′s you would need from eating sea food. Unfortunately, industrial pollution has changed the landscape, turning most of the world’s waters more or less toxic. Fish are now loaded with mercury, industrial toxins, PCBs and PDEs. The same goes for most of the oil that is made from these fish.

Thankfully, there is a sustainable source of animal-based omega-3 fats available, namely krill oil. Krill are very tiny shrimp-like creatures that exceed the number of all animals (including humans) in the world! Krill oil is also more readily absorbed than fish oil because krill fat is attached to phosphates. This means you need far less krill oil than you would fish.

Another bonus?

Krill oil contains antioxidants called astaxanthin that protect DHA and EPA fats until they are consumed.

These factors make krill oil the optimal choice to meet your omega-3 needs.

Vitamin K2 is CRUCIAL in Preventing Osteoporosis

Vitamin K can be classified as either K1 or K2:

  1. Vitamin K1: Found in green vegetables, K1 goes directly to your liver and helps you maintain a healthy blood clotting system. (This is the kind of K that infants need to help prevent a serious bleeding disorder.) It is also vitamin K1 that keeps your own blood vessels from calcifying, and helps your bones retain calcium and develop the right crystalline structure.
  2. Vitamin K2: Bacteria produce this type of vitamin K. It is present in high quantities in your gut, but unfortunately is not absorbed from there and passes out in your stool. K2 goes straight to vessel walls, bones, and tissues other than your liver. It is present in fermented foods, particularly cheese and the Japanese food natto, which is by far the richest source of K2.

Vitamin K2 can convert to K1 in your body, but there are some problems with this, which I will discuss shortly. As a supplement, K1 is less expensive, which is why it’s the form used for neonates.

Making matters even more complex, there are several different forms of vitamin K2.

MK8 and MK9 come primarily from dairy products. MK4 and MK7 are the two most significant forms of K2, and act very differently in your body:

  • MK4 is a synthetic product, very similar to vitamin K1, and your body is capable of converting K1 into MK4. However, MK4 has a very short half-life of about one hour, making it a poor candidate as a dietary supplement. After reaching your intestines, it remains mostly in your liver, where it is useful in synthesizing blood-clotting factors.
  • MK7 is a newer agent with more practical applications because it stays in your body longer; its half-life is three days, meaning you have a much better chance of building up a consistent blood level, compared to MK4 or K1.MK7 is extracted from the Japanese fermented soy product called natto. You could actually get loads of MK7 from consuming natto as it is relatively inexpensive, and is available in most Asian food markets. Few people, however, care for it’s smell and slimy texture and find it difficult to tolerate.

The evidence suggests that vitamin K2 is essential for your bone health, but it is a nutrient the vast majority of you do not get in adequate amounts from your diet.

How does vitamin K lead to bone health?

Osteocalcin is a protein produced by your osteoblasts (cells responsible for bone formation), and is utilized within the bone as an integral part of the bone-forming process. However, osteocalcin must be “carboxylated” before it can be effective. Vitamin K functions as a cofactor for the enzyme that catalyzes the carboxylation of osteocalcin.

Vitamin K2 has been found to be a far more effective “activator” of osteocalcin than K1.

There has been some remarkable research about the protective effects of vitamin K2 against osteoporosis:

  • A number of Japanese trials have shown that vitamin K2 completely reverses bone loss and in some cases even increases bone mass in people with osteoporosis .
  • The pooled evidence of seven Japanese trials show that vitamin K2 supplementation produces a 60 percent reduction in vertebral fractures and an 80 percent reduction in hip and other non-vertebral fractures .
  • Researchers in the Netherlands showed that vitamin K2 is three times more effective than vitamin K1 in raising osteocalcin, which controls the building of bone.

Although your body can convert K1 into K2, studies show that the amount of K2 produced by this process alone is insufficient. Even if you are consuming enough K1, your body uses most of it to make clotting factors, leaving little remaining for your bones.

In other words, your liver preferentially uses vitamin K1 to activate clotting factors, while most of your other tissues preferentially use K2.

Vitamin K2 has also been found to offer you other benefits—besides your bones!

Vitamin K2 is the biological glue that plugs calcium into your bone matrix. Dietary sources of K2 can be found in traditionally fermented foods such as tempeh, miso, natto and soy sauce..

Are You Getting Enough Vitamin K from Your Diet?

Eating lots of green vegetables will increase your vitamin K1 levels naturally, especially:

  • Kale
  • Spinach
  • Collard greens
  • Broccoli
  • Brussels sprouts

You can obtain all the K2 you’ll need (about 200 micrograms) by eating 15 grams of natto daily, which is half an ounce. However, natto is generally not pleasing to the Westerner’s palate, so the next best thing is a vitamin K2 supplement.

But remember, you must always take your vitamin K supplement with fat since it is fat-soluble and won’t be absorbed without it.

Although the exact dosing is yet to be determined, Dr. Vermeer recommends between 45 mcg and 185 mcg daily for adults. You must use caution on the higher doses if you take anticoagulants, but if you are generally healthy and not on these types of medications, I suggest 150 mcg daily.

Fortunately, you don’t need to worry about overdosing on K2—people have been given a thousand-fold “overdose” over the course of three years, showing no adverse reactions (i.e., no increased clotting tendencies).

Exercise to Prevent Bone Loss

Remember that bone is living tissue that requires regular physical activity in order to renew and rebuild itself.

Peak bone mass is achieved in adulthood and then begins a slow decline. Exercise is very important in maintaining healthy bone mass. Weight-bearing exercise is one of the most effective remedies against osteoporosis. The last thing you want to consider is to take a drug to improve your bone density, as without question, that is more likely to cause long-term harm than benefit.

Your bones are actually very porous and soft, and as you get older, your bones can easily become less dense and hence, more brittle. Especially if you are inactive.

Resistance training can combat this effect because as you put more tension on your muscles it puts more pressure on your bones, which then respond by continuously creating fresh, new bone.

In addition, as you build more muscle, and make the muscle that you already have stronger, you also put more constant pressure on your bones.

A good weight bearing exercise to incorporate into your routine (depending on your current level of fitness, of course) is a walking lunge, as it helps build bone density in your hips, even without any additional weights. However there is newer technology as discussed below that may even be better.

Discover Acceleration Training

Acceleration training exercise is based on Rhythmic Neuromuscular Stimulation (RNS) dating back to the 1960s when Professor W. Biermann, from the former East German Republic, described ‘cyclical vibrations’ capable of improving the condition of your joints relatively quickly.

As the theories of acceleration training exercise developed, Russian ballet dancers with minor muscle injuries such as Achilles tendonitis discovered that vibration aided the healing process. They also found that their muscular strength and jump height increased with only a quarter of the effort or time required by traditional training methods.

Since then many athletes have discovered the benefits of acceleration training exercise.

These results can be achieved now by using the ‘Power Plate’, which combines a series of exercises and stretches with cyclical vibrations designed to prevent mineral bone loss by adding mechanical load to the bone via the muscle and tendons.

Osteoporosis in Men

Here is something about osteoporosis in men you may not have realized: Men over the age of 50 are at greater risk for developing osteoporosis than prostate cancer. Men develop this disease because of a condition called hypogonadism, which may lead to shrinking by several inches. Risk factors in men include:

  • Alcoholism
  • Obesity
  • Smoking
  • Gastrointestinal disorders
  • Sedentary lifestyle
  • Lack of sunlight exposure

Men with pre-existing conditions such as asthma, emphysema, Crohn’s disease, herniated disks, and autoimmune disease taking steroids such as prednisone or cortisone are increasing their risk of developing osteoporosis that much further.

The Surprising Link Between Alzheimer’s Disease and Bone Loss

As I mentioned in a previous article, low bone mass has a surprising connection to Alzheimer’s disease.

In the study, researchers recorded bone mass measurements for 987 men and women with an average age of 76 years. They then followed them for up to 13 years and tracked who developed Alzheimer’s or dementia.

Results showed that women with the lowest bone mass measurements were more than twice as likely to develop Alzheimer’s or dementia as women with stronger bones.

If a woman of 70 years of age has lower bone mass, it means her exposure to estrogen may not have been as high as it should. Therefore, it seems estrogen loss plays a critical role in the development of osteoporosis as well as Alzheimer’s disease.

It’s Far Easier to Prevent Bone Loss than to Treat It

It’s true what Benjamin Franklin said, “An ounce of prevention is worth a pound of cure.” Now that you’re armed with the knowledge you need to make informed decisions about the prevention and healing of osteoporosis, you’re ready to take control of your health!

Related Articles / Categories:

Calcium

Vitamin K

Vitamin D

Gluten and Osteoporosis

Onion

Osteoporosis Drugs

Osteoporosis and Alzheimer’s Disease

Male Osteoporosis

Osteoporosis Prevention

General

Osteoporosis Drugs are Very Dangerous

This “Miracle Drug” Could Nearly Double Your Risk of Cancer

Posted By Dr. Mercola | September 24 2010 | 88,190 views

osteoporosis drugOral bisphosphonate osteoporosis drugs, which include such Actonel, Boniva, and Fosamax, could be associated with an approximately twofold increased risk of esophageal cancer.

A new study showed that long-term users of the drugs had nearly double the risk for the rare but deadly cancer.

Concerns about a link between bisphosphonates and esophageal cancer first reached the public a year and a half ago, when an FDA report cited 23 cases of the cancer in Fosamax users in the U.S., and another 31 cases in Europe and Japan.

WebMD reports:

“The … analysis included close to 3,000 patients with cancer of the esophagus, 2,000 patients with stomach cancer, and 10,600 patients with colorectal cancer diagnosed between 1995 and 2005. Each cancer case was compared with five people without cancer matched for age and sex.”

Sources:

Dr. Mercola’s Comments:

Osteoporosis is a very common problem, affecting one in three women and one in five men over the age of 50.

It’s characterized by porous and fragile bones, increasing your risk of fractures, most often your hips, spine and wrists. Interestingly, nearly 75 percent of all hip fractures occur in women, and hip fractures, worldwide, rose 25 percent in just ten years, between 1990 and 2000.

All in all, osteoporosis is a major health risk for nearly 30 million Americans, in large part because many are clueless about how to prevent it.

As a result, osteoporosis has become yet another boon for the pharmaceutical industry. According to a 2010-2025 Osteoporosis World Market Report, the condition generated pharmaceutical revenues of over $12 billion worldwide in 2009.

Unfortunately, osteoporosis drugs are now also increasingly prescribed to women with osteopenia, a natural thinning of the bones as you get older, even though no conclusive benefit has been found for this condition.

The Conventional Approach – A Dangerous First Line Defense

There are a variety of drugs on the market to combat bone loss, but the first line of therapy typically includes oral bisphosphonate drugs, such as:

  • Fosamax
  • Didronel
  • Boniva
  • Actonel
  • Reclast

In June of this year the US FDA also approved a new type of injectable medication for the treatment of postmenopausal osteoporosis, as reported by CNN.

The drug, called Prolia, is a “biologic” medication, meaning it contains genetically engineered human proteins instead of synthetic chemicals.

The Los Angeles Times did a write-up on the drug, stating that:

“Prolia is a little bit different from the other osteoporosis drugs in that it’s a complicated biological molecule — an antibody — that was specifically designed to bind to, and inactivate, a protein in the body involved in bone metabolism.

That protein, RANKL, stimulates the breakdown of bone tissue during normal bone turnover. By inhibiting RANKL, Prolia suppresses bone breakdown and prevents bone loss.”

However, despite being entirely different from bisphosponates, some of the identical health problems have already surfaced with Prolia, such as jaw osteonecrosis (which I’ll discuss in a moment).

This is no surprise as it essentially works the same way as the bisphosphonates, as it prevents the normal dynamic building and breakdown of bone. It slows down the normal resorption so the bone becomes denser but not any stronger.

Other side effects of Prolia include “skin infections, some serious enough to require hospitalization, and other infections, such as in the ears, urinary tract and the heart. Back pain and pain in the muscles and bones have been reported, as have elevated cholesterol levels,” the LA Times reports.

Time will tell just how poor a choice this drug really is, but I can virtually guarantee you that, just like the bisphosphonates, it will not serve your long-term best interest.

Increased Cancer Risk Confirmed Among Bisphosphonates Users

According to this latest study published in the journal BMJ, long-term use of oral bisphosphonate drugs may double your risk of esophageal cancer – a rare but deadly cancer.

The authors concluded that:

“The risk of esophageal cancer increased with 10 or more prescriptions for oral bisphosphonates and with prescriptions over about a five year period.

In Europe and North America, the incidence of esophageal cancer at age 60-79 is typically 1 per 1000 population over five years, and this is estimated to increase to about 2 per 1000 with five years’ use of oral bisphosphonates.”

This link came to light early last year, when a brief report in the New England Journal of Medicine revealed that the FDA had received 23 reports of esophageal cancer possibly linked to the drug.

The risk of contracting esophageal cancer from these drugs may still be low enough for many people to take the risk, but there are other, far more common side effects that can be just as devastating.

Side Effects of Osteoporosis Drugs can Be Far Worse than Brittle Bones…

Osteoporosis drugs have become increasingly well-known for their dangerous side effects, many of which could easily be worse than your original concern.

Acid reflux and related esophageal inflammation were a couple of the side effects that quickly became apparent when these drugs hit the market. This is why you’re instructed to take them with food and avoid lying down shortly after taking them.

But as I predicted over a decade ago, that’s just the beginning of the health nightmare these drugs can bring about.

Since their release, bisphosphonate drugs have also become associated with:

  • Hypocalcemia (blood calcium levels are too low)
  • Serious eye inflammation and possible blindness
  • Severe musculoskeletal pain
  • Stomach ulcers – particularly when taken together with anti-inflammatory drugs.In one study, 8 percent of participants taking Fosamax and 12 percent of those receiving the anti-inflammatory Naprosyn developed stomach ulcers. But when the two drugs were taken in combination, the rate of stomach ulcers rose to a whopping 38 percent.This is important, as many elderly, particularly women, are likely to suffer from both arthritis and osteoporosis, increasing the likelihood of bisphosphonates and anti-inflammatory drugs being taken at the same time.
  • Liver damage –Although the mechanism is still unknown, researchers believe drugs like Fosamax may inhibit the synthesis of cholesterol in your liver, which may alter liver function.Regardless of the mechanism, if you’re taking Fosamax or related bisphosphonate drugs you need to beware of the possibility of liver dysfunction, and your doctor should monitor you properly for it.
  • Kidney failure (renal failure)
  • Atrial fibrillation — Women who have used Fosamax are nearly twice as likely to develop atrial fibrillation (quivering of your heart’s upper chambers), which is the most common kind of chronically irregular heartbeatOne study published in the Archives of Internal Medicine found that Fosamax was associated with an 86 percent higher risk of atrial fibrillation compared to those who had never used the drug.Atrial fibrillation can cause palpitations, fainting, fatigue, or congestive heart failure. It can also lead to embolic strokes.
  • Thigh bone (femur) fractures – Although you’ve only started hearing about this recently, the FDA asked Merck (the maker of Fosamax) to “add information about the report of femur fractures” to the medication’s package insert back in 2008, according to an ABC News report.Sixteen months later they finally added it to the list of fine print side effects, but neither Merck nor the FDA properly informed doctors and patients of this newfound risk.According to a recent report by a US panel of experts reviewing the evidence of increased risk of unusual femur fractures, 94 percent of patients who had experienced a femur break had been on bisphosphonate drugs. Most of them had taken the drugs longer than five years.More than half of those who broke their thigh bones had reported groin or thigh pain for a period of weeks or months before fractures occurred.In addition, “more than a quarter of patients who experienced atypical femur fractures in one leg experienced a fracture in the other leg as well,” Canadian CTV reports.
  • Osteonecrosis of your jaw bone (jaw bone death) — This is a serious condition that can also cause disfiguration as the bone in your jaw dies and begins to decay.Symptoms include jaw pain, infection, and loosening of your teeth. However, some people experience no symptoms until they suddenly notice exposed bone. If you’ve had teeth extracted, or wear full dentures, you may also be at greater risk.Interestingly, an animal study published in the June issue of Journal of Bone and Mineral Research concluded that osteonecrosis of the jaw may involve the interaction between bisphosphonate drugs and vitamin D deficiency! As you will see below, optimizing your vitamin D levels is imperative for healthy bones, and this finding further strengthens that recommendation.

How Osteoporosis Drugs WEAKEN Rather than Strengthen Your Bones Over Time

It’s important to realize that, over time, these drugs will only worsen, not improve, your condition, because all you’re doing is fooling your body to produce a denser bone that is actually weaker – as evidenced by increasing rates of thigh bone fractures.

It’s ironic, to say the least, that these drugs, prescribed to treat brittle bones and prevent fractures, actually produce weaker bones and cause more unusual fractures that are exceedingly difficult to recuperate from.

Healthy bones maintain their strength from a continual process of bone breakdown and bone rebuilding. Osteoclasts are cells that break down bone, and osteoblasts are the cells that rebuild it.

Healthy bone undergoes a dynamic process of cyclical removal of unhealthy bone and replacement with new bone. This is how they remain strong.

In osteoporosis, the net rate of bone resorption (breakdown) exceeds the rate of bone formation, which results in a decrease in bone mass.

But it’s important to realize that Fosamax and similar drugs do NOT build any new bone. Rather they are metabolic poisons that kill off your osteoclasts, which halts the normal bone repair process since you now lack the cells that break bone down.

Your bones will indeed get denser. However, denser bones are NOT stronger, which is the part they don’t tell you. Eventually your bones become weaker and more prone to fracture.

In women who have been taking a bisphosphonate-type drug for five or more years, their bones have literally lost the ability to regenerate and this is why many may be faced with more brittle bones and fractures.

12 Steps to Optimal Bone Health

It’s tragic that drugs like Fosamax continue to be touted as the answer to osteoporosis, because nothing could be further from the truth.

These simple guidelines can help you maintain, or increase, your bone strength safely and naturally, without the use of drugs that might cause you even further harm:

  1. Eat a healthful diet based on your body’s unique nutritional type.Eating high quality, organic, biodynamic, locally-grown food will naturally increase your bone density and decrease your risk of developing osteoporosis. If you find it difficult to eat the recommended amount of vegetables you need daily, you can try vegetable juicing.One food in particular that is worth mentioning are onions, which are high in gamma-glutamyl peptides that have been shown to increase bone density.Also remember that you need high quality protein like organic free-range eggs and grass-fed meats, because amino acids are part of your bone matrix. If you don’t consume enough of specific amino acids your body can’t form strong, dense bones.
  2. Avoid processed foods. If you eat a diet full of processed foods, it will produce biochemical and metabolic conditions in your body that will decrease your bone density, so avoiding processed foods is a first step in the right direction.
  3. Consume a healthy balance between omega-6 and omega-3 fats. Most everyone needs to take a high quality, animal-based omega 3 fat. I recommend krill oil, as I believe it’s a superior source of omega 3’s. You’ll also want to reduce or eliminate the amount of processed vegetable oils you consume, such as corn, canola, safflower, and soy oil.
  4. Avoid gluten, a grain protein that has been shown to decrease bone density. Gluten is found in wheat, barley, rye, oats and spelt.
  5. Avoid soda and sugar, particularly fructose, which increase bone damage by depleting your bones of calcium.
  6. Optimize your vitamin D levels, ideally through proper amounts of sun exposure. Vitamin D builds your bone density by helping your body absorb calcium.
  7. Supplement with vitamin K2 if you are not getting enough from food alone. Fermented foods, such as natto, typically have the highest concentration of vitamin K found in the human diet and can provide several milligrams of vitamin K2 on a daily basis.Vitamin K2 serves as the biological “glue” that helps plug the calcium into your bone matrix and is crucial for preventing osteoporosis. I recommend taking about 150 mcg per day.
  8. Make sure your diet includes sufficient amounts of magnesium, manganese, zinc, silicon and boron, or take them as supplements.  The best form of calcium is to consume raw dairy regularly. Additionally, cheese is a good source of vitamin K2.
  9. Replace your calcium supplements with natural salts – Dr. Robert Thompson M.D. wrote an entire book, The Calcium Lie, addressing this important issue. One of the tenets of his book is that bone is composed of at least a dozen minerals, and if you focus exclusively on calcium supplementation you are likely going to worsen your bone density, and will actually increase your risk of osteoporosis!Dr. Thompson believes that the overconsumption of calcium in the goal of preventing osteoporosis creates other mineral deficiencies and imbalances that will also increase your risk of heart disease, kidney stones, gallstones, osteoarthritis, hypothyroidism, obesity and type 2 diabetes.He believes almost everyone needs trace minerals, not just calcium, because you simply cannot get all the nutrients you need through food grown in mineral depleted soils. Dr. Thompson believes unprocessed natural salts, such as Himalayan salt, are one of the best sources of these ionic trace minerals.
  10. Avoid steroids, especially if you have asthma or any other autoimmune disease, as they increase your risk for osteoporosis. Steroids are known to destroy bone density by impairing the cells that build bone (osteoblasts).
  11. Exercise. Studies show that exercise is just as important to your bone health as eating a calcium-rich diet. Strength-building exercises like weight training are especially helpful here.
  12. Consider natural progesterone, which can increase your bone strength and density by serving as a growth promoter for the osteoblasts (the cells that build bone).

I will be going into far more detail in the future, but the sex hormones ideally should be applied as a trans mucosal cream, applied in the vaginal labia area or rectum. They should not be applied on your skin and clearly should not be swallowed, so this would also eliminate sublingual drops as it is nearly impossible to avoid swallowing some of the drops.

Of course, it would be wise to have the other basics in place such as adequate amounts of calcium, zinc, magnesium, vitamin D and copper, in addition to exercise and avoidance of foods that will damage your bone, such as fructose and gluten.

It’s important to realize, however, that only natural progesterone will do here. The synthetic version, Provera, will not provide this bone-building benefit. For more on progesterone, please review Complications Regarding Progesterone Cream.

Vibration Physical Exercises as the Rehabilitation in Gerontology

platformVibration biomechanical stimulation as the physiological basis of vibration physical exercises (whole body vibration) causes reflecting muscle contractions like tonic vibration reflex. This type of intervention leads to high intensive stimulation of proprioceptors as called muscle spindles which result in alteration in parameters of activity and developments of human physiological functions. This type of training has broad positive influence on organism. Acceleration physical exercises improve muscle performance, flexibility, nervous function, significantly increase bone mineral density, physiological secretion of anabolic hormones, growth and anti-aging factors; normalize/decrease cortisol as anti-stress effect and are beneficial for balance and mobility as well. It is showed acceleration training caused by vibration stimulus is beneficial for people suffering from osteoporosis and obesity, for rehabilitation of nervous and motor function in patients with Parkinson’s disease, multiple sclerosis and stroke. PMID: 19947400 [PubMed - in process]

Pub Med. Gov

U.S. National Library of Medicine

National Institutes of Health

Whole Body Vibration: Helping those with Osteoporosis

Dtsch Med Wochenschr. 2009 Jul;134(30):1511-6. Epub 2009 Jul 14.

[Effect of whole body vibration exercise on osteoporotic risk factors]

[Article in German]

von Stengel S, Kemmler W, Mayer S, Engelke K, Klarner A, Kalender WA.

Institut für Medizinische Physik, Friedrich-Alexander Universität Erlangen-Nürnberg. simon.von.stengel@imp.uni-erlangen.de

BACKGROUND AND OBJECTIVE: Whole body vibration (WBV) training is a new approach which is currently discussed in the context of reducing the risk of osteoporotic fractures. The study was undertaken to determine the effect of one-year WBV exercise on bone mineral density (BMD) and the number of falls. METHODS: 151 postmenopausal women (68.5 +/- 3.1 years) were randomly assigned to three groups: (1) conventional (multifunctional) training (TG); (2) multifunctional training including WBV (VTG); (3) wellness-control group (CG). The training groups performed multifunctional training twice weekly (60 min; dancing aerobics, balance training, functional strength training). In the last 15 min of each session, leg strength exercises on vibration platforms were performed. The plates were switched on only in the VTG. The CG performed a low intensity gymnastic and relaxation programme (4 x 10 sessions of 60 min). BMD was measured at the hip and lumbar spine at baseline and after 12 months with the DXA method. Falls were recorded daily with the calendar method in a fall log. RESULTS: An increase in BMD at the lumbar spine was measured after one year in both training groups (VTG: + 1.17 +/- 2.4 % vs. TG: + 1.73 +/- 2.4 %). The difference between the TG and the CG was significant (p < .05). Regarding the hip region a loss was noted in the CG (- 0.9 +/- 2.5), whereas the BMD stayed stable in the training groups (TG: – 0.3 %; VTG: + 0.1 %). The fall rate was significantly lower in VTG compared to CG (0.43 falls/person/year (VTG) vs. 1.14 (CG). CONCLUSION: The multifunctional training resulted in a gain of BMD at the lumbar spine. Vibration training did not enhance the effect on bone but significantly reduced falls.

PMID: 19603365 [PubMed - indexed for MEDLINE]

PubMed.Gov

U.S. National Library of Medicine

National Institutes of Health

Whole Body Vibration and Bone Growth

platformLow-level mechanical vibrations can influence bone resorption and bone formation in the growing skeleton.

Xie L, Jacobson JM, Choi ES, Busa B, Donahue LR, Miller LM, Rubin CT, Judex S.

Department of Biomedical Engineering, Psychology A, 3rd Floor, State University of New York at Stony Brook, Stony Brook, NY 11794-2580, USA.

Short durations of extremely small magnitude, high-frequency, mechanical stimuli can promote anabolic activity in the adult skeleton. Here, it is determined if such signals can influence trabecular and cortical formative and resorptive activity in the growing skeleton, if the newly formed bone is of high quality, and if the insertion of rest periods during the loading phase would enhance the efficacy of the mechanical regimen. Eight-week-old female BALB/cByJ mice were divided into four groups, baseline control (n = 8), age-matched control (n = 10), whole-body vibration (WBV) at 45 Hz (0.3 g) for 15 min day(-1) (n = 10), and WBV that were interrupted every second by 10 of rest (WBV-R, n = 10). In vivo strain gaging of two additional mice indicated that the mechanical signal induced strain oscillations of approximately 10 microstrain on the periosteal surface of the proximal tibia. After 3 weeks of WBV, applied for 15 min each day, osteoclastic activity in the trabecular metaphysis and epiphysis of the tibia was 33% and 31% lower (P <0.05) than in age-matched controls. Bone formation rates (BFR.BS(-1)) on the endocortical surface of the metaphysis were 30% greater (P <0.05) in WBV than in age-matched control mice but trabecular and middiaphyseal BFR were not significantly altered. The insertion of rest periods (WBV-R) failed to potentiate the cellular effects. Three weeks of either WBV or WBV-R did not negatively influence body mass, bone length, or chemical bone matrix properties of the tibia. These data indicate that in the growing skeleton, short daily periods of extremely small, high-frequency mechanical signals can inhibit trabecular bone resorption, site specifically attenuate the declining levels of bone formation, and maintain a high level of matrix quality. If WBV prove to be efficacious in the growing human skeleton, they may be able to provide the basis for a non-pharmacological and safe means to increase peak bone mass and, ultimately, reduce the incidence of osteoporosis or stress fractures later in life.

PMID: 16824816 [PubMed - indexed for MEDLINE]